Antimalarial studies on 4,4-diaminodiphenyl sulfone (DDS) and repository sulfones in experimental animals.
نویسنده
چکیده
منابع مشابه
Chemotherapy of murine leprosy. V. The effects of various combinations of 4, 4 -diaminodiphenyl sulfone (DDS), streptomycin and isoniazid on mouse leprosy.
In previous communications (3-5) I have reported, among other things, that 4-4'-diaminodiphenyl sulfone (DDS), streptomycin, and isoniazid (isonicotinic acid hydrazide) possess definite therapeutic activity in mouse leprosy, and that the combination of DDS and streptomycin showed an additive effect. The effects of various combinations of DDS, streptomycin and isoniazid on mouse leprosy are repo...
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A cell-impermeable diffusion chamber technique has been developed that lends itself to growth studies of Mycobacterium lepraemurium. This technique, in which the organism grows within macrophage cultures inside the chambers that are maintained on monolayer cultures of macrophages, provides a method for a strict in vitro evaluation of antileprosy drugs without the influence of a multiplicity of ...
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Linear immunoglobulin A (IgA) bullous dermatosis (LABD) is an autoimmune mucocutaneous disease characterized by subepidermal blistering induced by IgA autoantibodies against several autoantigens in the basal membranous zone of the skin and mucosal tissue. Although diaminodiphenyl sulfone (DDS), also known as dapsone, is generally recognized as the first-line therapy for LABD, DDS can induce sev...
متن کاملSupramolecular Organization of Nonstoichiometric Drug Hydrates: Dapsone
The observed moisture- and temperature dependent transformations of the dapsone (4,4'-diaminodiphenyl sulfone, DDS) 0. 33-hydrate were correlated to its structure and the number and strength of the water-DDS intermolecular interactions. A combination of characterization techniques was used, including thermal analysis (hot-stage microscopy, differential scanning calorimetry and thermogravimetric...
متن کاملCuring behavior and thermal properties of trifunctional epoxy resin cured by 4, 4’-diaminodiphenyl sulfone
A novel trifunctional epoxy resin 4-(3, 3-dihydro-7-hydroxy-2, 4, 4-trimethyl-2H-1-benzopyran-2-yl)-1, 3-benzenediol glycidyl (shorted as TMBPBTH-EPOXY) was synthesized in our lab to improve thermal performance. Its curing behavior and performance were studied by using 4, 4′-diaminodiphenyl sulfone (DDS) as hardener with the mass ratio of 100:41 of TMBPBTH-EPOXY and DDS. The curing activation e...
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ورودعنوان ژورنال:
- International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
دوره 35 4 شماره
صفحات -
تاریخ انتشار 1967